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[慢性尿毒症患者透析血清中抗 N 样抗体的发生率]

[Incidence of the anti-N-like antibodies in the serum of patients dialyzed for chronic uremia].

作者信息

Illés M, Gál G

机构信息

Szent-Györgyi Albert Orvostudományi Egyetem, Szeged.

出版信息

Orv Hetil. 1991 Nov 17;132(46):2531-2, 2535-6.

PMID:1811202
Abstract

The authors examined the serum of 164 hemodialysed chronic uremic patients for the detection of anti-N-like antibodies in two time intervals (in 1982 and 1988). The hemodialysis treatment was done in both intervals with regenerated, formaline-sterilized capillary dialysers. In 1982 antibodies could be detected in 5 out of 44 patients (11.3%) while in 1988 the ratio was 3 out of 120 (2.5%). The control group consisted of 40 healthy blood donors and 27 such dialysed patients who were treated only with new, ethylene oxide-sterilized single use capillary dialysers. The special cold agglutinine was not detectable in the serum of the subjects of the control group.

摘要

作者在两个时间段(1982年和1988年)检测了164例慢性尿毒症血液透析患者的血清,以检测抗N样抗体。两个时间段均使用经甲醛消毒再生的毛细血管透析器进行血液透析治疗。1982年,44例患者中有5例(11.3%)检测到抗体,而1988年这一比例为120例中的3例(2.5%)。对照组包括40名健康献血者和27名仅使用环氧乙烷消毒的一次性新毛细血管透析器进行透析治疗的患者。对照组受试者的血清中未检测到特殊冷凝集素。

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