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[使用定量脑电图评估帕金森病的额叶受累及皮质和皮质下退变]

[Frontal lobe involvement and cortical and subcortical deterioration in Parkinson's disease evaluated using quantified electroencephalography].

作者信息

García-Mas A, Rosiñol Far A, Roca Bennasar M, Llinas J, Rossello Mir J

机构信息

Departamento de Psicología, Universitat de les Illes Balears.

出版信息

Arch Neurobiol (Madr). 1991 Nov-Dec;54(6):303-10.

PMID:1811461
Abstract

Quantified electroencephalography (EEGq) by means the Fast Fourier Transformed system (FFT) was carried out on two groups of patients with idiopathic Parkinson's Disease (PD). The first one was with symptoms of cortical deterioration, and the second group consisting of subjects without signs of cortical impairment. The study of the specific EEGq indices has led to the establishment of parameters which establish differences between these two groups. Specifically, a difference has been found with regard to the total potentials of delta and alpha frequency bands; alpha/theta index; posterior activities; changes in the lobular antero-posterior of delta and alpha rhythms; and in the distribution of the spatialization index of alpha rhythm. We discuss the implications of this electrophysiological differentiation between the two groups, regarding the possible frontal lobe affection in the subcortical dementiation of the Parkinson's disease.

摘要

通过快速傅里叶变换系统(FFT)对两组特发性帕金森病(PD)患者进行了定量脑电图(EEGq)检查。第一组有皮质退化症状,第二组由无皮质损伤迹象的受试者组成。对特定EEGq指标的研究已得出能够区分这两组差异的参数。具体而言,在δ和α频段的总电位、α/θ指数、后部活动、δ和α节律的小叶前后变化以及α节律空间化指数的分布方面发现了差异。我们讨论了两组之间这种电生理差异的意义,涉及帕金森病皮质下痴呆中可能存在的额叶病变。

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