Pérez-Comas A
Escuela de Medicina de Ponce, Condado, Santurce, P.R. 00907.
Bol Asoc Med P R. 1991 Nov;83(11):489-95.
Diabetes mellitus is a heterogeneous disease that might present as insulin-dependent (type I), non-insulin-dependent (type II), and other forms associated with other endocrine and genetic conditions, as well as those secondary to different infiltrative or destructive pancreatic diseases, parasitosis and post-pancreatectomy patients. Insulin-dependent diabetes mellitus is mainly associated to immunological problems, probably by derangement caused by external factors, such as viral infections that favor destruction of beta cells of the pancreas. On type II diabetes the hereditary component is more important and does not present immunological problems. Different etiological considerations are included, as well as associated genetic markers that are described in the text.
糖尿病是一种异质性疾病，可能表现为胰岛素依赖型（I型）、非胰岛素依赖型（II型），以及与其他内分泌和遗传状况相关的其他形式，还有继发于不同浸润性或破坏性胰腺疾病、寄生虫病以及胰腺切除术后患者的糖尿病。胰岛素依赖型糖尿病主要与免疫问题相关，可能是由外部因素（如病毒感染）导致的紊乱引起的，这些因素会促使胰腺β细胞被破坏。II型糖尿病中遗传因素更为重要，且不存在免疫问题。文中还包括了不同的病因学考量以及相关的遗传标记。
