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献血者血清中抗疟抗体与HIV感染血清反应性的关系。

Antimalarial antibody in relation to seroreactivity for HIV infection in sera from blood donors.

作者信息

Chattopadhya D, Kumari S, Chatterjee R, Verghese T

机构信息

National Institute of Communicable Diseases, Delhi.

出版信息

J Commun Dis. 1991 Sep;23(3):195-8.

PMID:1812166
Abstract

A total of 74 specimens from blood donors showing evidence of HIV infection comprising of 40 positive by both ELISA and Western Blot (true positive), 16 positive by ELISA but negative by Western Blot (false positive) and 18 specimens positive by ELISA but showing indeterminate bands in Western Blot were screened for anti-malarial antibody. The prevalence of antimalarial antibody was noted as 62.5%, 56.3% and 66.6% respectively in these groups. None of these groups had any difference in the prevalence of antimalarial antibody with the group of 60 specimens negative for HIV infection by both ELISA as well as Western Blot (true negative) which had a prevalence of antimalarial antibody as 53.3%. The mean titre of antimalarial antibody in the above categories of specimens positive for HIV infection also did not show any difference with that of true negative group. These findings point out that antimalarial antibody does not influence the serological positivity for HIV infection.

摘要

对74份来自献血者且显示有HIV感染迹象的标本进行了抗疟抗体筛查。这些标本包括40份ELISA和免疫印迹均为阳性的(真阳性)、16份ELISA阳性但免疫印迹阴性的(假阳性)以及18份ELISA阳性但免疫印迹显示不确定条带的标本。这些组中抗疟抗体的流行率分别为62.5%、56.3%和66.6%。这些组中抗疟抗体的流行率与60份ELISA和免疫印迹均为HIV感染阴性的标本组(真阴性)没有差异,真阴性组抗疟抗体的流行率为53.3%。上述HIV感染阳性的各类标本中抗疟抗体的平均滴度与真阴性组也没有差异。这些发现指出,抗疟抗体不会影响HIV感染的血清学阳性结果。

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