Gabriel M, Albani M
Eur J Pediatr. 1976 Jul 12;122(4):257-61. doi: 10.1007/BF00481505.
Changes in respiration and heart rate during sleep states have been recorded by a polygraphic device in healthy preterm infants. Cardiac slowing/bradycardia often coincide with respiratory arrest/apnea. Bradycardia starts early during apneic spells. The incidence of respiratory arrest and cardiac slowing and their simultaneous occurrence is significantly increased by the active or REM sleep state. The physiologic, inhibitory mechanisms of active sleep suggest a neurogenic etiology of episodes of cardiac slowing/bradycardia and/or respiratory arrest/apnea in prematures.
通过多导记录仪记录了健康早产儿睡眠状态下呼吸和心率的变化。心脏减慢/心动过缓常与呼吸停止/呼吸暂停同时出现。心动过缓在呼吸暂停发作早期就开始出现。活跃睡眠或快速眼动睡眠状态会显著增加呼吸停止和心脏减慢及其同时发生的发生率。活跃睡眠的生理抑制机制提示早产儿心脏减慢/心动过缓发作和/或呼吸停止/呼吸暂停发作存在神经源性病因。
