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[妊娠期肝内胆汁淤积症:发病率、临床过程、并发症]

[Intrahepatic cholestasis in pregnancy: incidence, clinical course, complications].

作者信息

Roncaglia N, Trio D, Roffi L, Ciarla I, Tampieri A, Scian A, Bottino S

机构信息

Istituto di Scienze Biomediche S. Gerardo dei Tintori, Monza.

出版信息

Ann Ostet Ginecol Med Perinat. 1991 May-Jun;112(3):146-51.

PMID:1812797
Abstract

From January 1st, 1984 to December 31st, 1988 67 cases of cholestasis during pregnancy (frequency rate 0.7%) have been reviewed. In the 79% of the cases cholestasis arose after the 32nd week. Preterm deliveries were 19.5% and cesarean sections were 19.4%. Perinatal mortality was 30%. Pregnancy complicated by cholestasis is a high risk problem in obstetrics. An attempt to show a clinical management is exposed.

摘要

1984年1月1日至1988年12月31日期间,对67例妊娠期胆汁淤积症患者(发病率为0.7%)进行了回顾性研究。79%的病例胆汁淤积发生在孕32周之后。早产率为19.5%,剖宫产率为19.4%。围产儿死亡率为30%。妊娠期合并胆汁淤积症是产科的一个高危问题。本文展示了一种临床管理方法。

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Fetal mortality associated with cholestasis of pregnancy and the potential benefit of therapy with ursodeoxycholic acid.妊娠肝内胆汁淤积症相关的胎儿死亡率及熊去氧胆酸治疗的潜在益处。
Gut. 1995 Oct;37(4):580-4. doi: 10.1136/gut.37.4.580.