Parton R G
European Molecular Biology Laboratory, Cell Biology Program, Heidelberg, Germany.
Semin Cell Biol. 1991 Dec;2(6):387-95.
Recent biochemical and morphological studies using the MDCK cell line have provided insights into the organization of the endocytic pathways in an epithelial cell. The cytoskeletal organization of these cells has been described and evidence for the involvement of microtubules in facilitating endocytic traffic has been obtained. The findings with this model system are compared to results from in vivo studies of the endocytic pathways from the surface domains of specialized epithelial cells and to studies of endocytosis in neurons.
最近利用MDCK细胞系进行的生物化学和形态学研究，为上皮细胞内吞途径的组织提供了见解。这些细胞的细胞骨架组织已被描述，并且已经获得了微管参与促进内吞运输的证据。将该模型系统的研究结果与来自特殊上皮细胞表面区域内吞途径的体内研究结果以及神经元内吞作用的研究结果进行了比较。
