使用固定在海藻酸钙凝胶珠中的丝状真菌对13-乙基-4-烯-3,17-二酮进行15α-羟基化反应。
15 alpha-hydroxylation of 13-ethyl-gon-4-ene-3,17-dione using a hyphal fungus immobilized in calcium alginate gel beads.
作者信息
Schlosser D, Schmauder H P
机构信息
Institut für Mikrobiologie, Biologische Fakultät, Friedrich-Schiller-Universität Jena.
出版信息
J Basic Microbiol. 1991;31(5):385-90. doi: 10.1002/jobm.3620310518.
PMID:1813625
Abstract
Calcium alginate-entrapped mycelium of Penicillium raistrickii i 477 was used for the 15 alpha-hydroxylation of 13-ethyl-gon-4-ene-3,17-dione. The system was tested in 10 batches during 40 days of operation, the catalytic activity could be completely regenerated by incubation in a nutrient medium between several batches.
摘要
用藻酸钙包埋的赖氏青霉i 477菌丝体用于13-乙基-4-烯-3,17-二酮的15α-羟基化反应。该系统在40天的运行期间分10批进行测试，几批之间通过在营养培养基中培养可使催化活性完全再生。
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