在β-环糊精存在的情况下，用赖氏青霉的游离细胞和固定化细胞进行甾体羟基化反应。
Steroid hydroxylation with free and immobilized cells of Penicillium raistrickii in the presence of beta-cyclodextrin.
作者信息
Schlosser D, Irrgang S, Schmauder H P
机构信息
Friedrich-Schiller-Universität Jena, Biologische Fakultät, Institut für Mikrobiologie, Lehrstuhl Technische Mikrobiologie, Federal Republic of Germany.
出版信息
Appl Microbiol Biotechnol. 1993 Apr;39(1):16-20. doi: 10.1007/BF00166841.
Free and Ca-alginate-immobilized cells of Penicillium raistrickii i 477 were used for 15 alpha-hydroxylation of 13-ethyl-gon-4-en-3,17-dione. The product formation of both free and immobilized cells was increased in the presence of beta-cyclodextrin, in comparison with reactions carried out in the presence of methanol. Application of beta-cyclodextrin led to increasing solubility of the steroid substrate. The fungus was able to utilize beta-cyclodextrin as a carbon source.
雷氏青霉i 477的游离细胞和钙藻酸盐固定化细胞用于13-乙基-4-烯-3,17-二酮的15α-羟基化反应。与在甲醇存在下进行的反应相比，在β-环糊精存在下，游离细胞和固定化细胞的产物生成量均有所增加。β-环糊精的应用提高了甾体底物的溶解度。该真菌能够利用β-环糊精作为碳源。
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