Kobayashi S, Iwase H, Matsuo K, Fukuoka H, Ito Y, Masaoka A
Second Department of Surgery, Nagoya City University Medical School, Japan.
Jpn J Surg. 1991 Sep;21(5):494-8. doi: 10.1007/BF02470984.
All cases of primary adrenocortical tumors, including those found incidentally, recorded in the Pathological Autopsy Case Annuals of Japan during a 12 year period from 1973 to 1984 were surveyed. Age- and sex-specific incidences of lesions were estimated from the population, mortality and autopsy statistics for the same period. There were 101 adenomas, 77 of which were presumed to be non-functional, and 222 carcinomas. The age-specific distribution profiles of both the benign and malignant tumors showed single peaks in the sixties and could not be distinguished from one another. The estimated age-specific distribution of morbidity of the non-functional adenomas showed a peak at about 10 years younger than that found in the autopsy records, although it was again similar to that of carcinoma derived from various clinical reports. The morbidity of the non-functional adenomas per 100,000 population was almost equal to that of breast cancer in Japan, being highest in the fifties age group with more than 4,000 people a year being suggested to have adenoma in this age bracket.
对1973年至1984年这12年间记录在《日本病理尸检病例年鉴》中的所有原发性肾上腺皮质肿瘤病例进行了调查，包括那些偶然发现的病例。根据同期的人口、死亡率和尸检统计数据，估算了不同年龄和性别的病变发病率。其中有101例腺瘤，其中77例被认为是非功能性的，还有222例癌。良性和恶性肿瘤的年龄特异性分布曲线在60多岁时均呈现单峰，且彼此无法区分。非功能性腺瘤的年龄特异性发病率估算显示，其峰值比尸检记录中的峰值约早10年，不过这再次与各种临床报告中癌的发病率相似。在日本，每10万人中非功能性腺瘤的发病率几乎与乳腺癌相当，在50多岁年龄组中发病率最高，每年该年龄组中有超过4000人被认为患有腺瘤。
