Xu B, Zhang D, Su W, Xiao S
Shanghai Technical Teacher's College.
Wei Sheng Wu Xue Bao. 1991 Dec;31(6):473-8.
Fecal specimens from 10 colorectal cancer, 1 duodenum diverticulosis and 2 healthy adults were examined. Nine fecal enrichments contained Methanobrevibacter. The percentage of methanogen positive individuals was 69% Methanobrevibacter were isolated from fecal enrichments of 4 colorectal cancer and 1 duodenum diverticulosis. The percentage of breath methane positive individuals and methane production had significantly increased in colorectal cancer patients. It will be hopeful that methane production in breath samples at the end of exhalation will became a rapid, simple and non-penetrative method for monitoring precancerous colonic or rectal carcinogenesis and monitoring the relapse of individuals with carcinosectomy.
对10例结直肠癌患者、1例十二指肠憩室病患者和2名健康成年人的粪便样本进行了检测。9份粪便富集培养物中含有短双歧杆菌。产甲烷菌阳性个体的比例为69%。从4例结直肠癌患者和1例十二指肠憩室病患者的粪便富集培养物中分离出了短双歧杆菌。结直肠癌患者呼出气甲烷阳性个体的比例和甲烷产量显著增加。呼气末呼出气样本中的甲烷产生有望成为一种快速、简单且无创的方法,用于监测结直肠癌或直肠癌前病变以及监测接受癌切除术患者的复发情况。