Caimi G, Contorno A, Serra A, Lo Presti R, Grifo G, D'Asaro S, Catania A, Sarno A, Cerasola G
Insegnamento di Fisiopatologia del Ricambio, Università degli Studi, Palermo, Italy.
Microcirc Endothelium Lymphatics. 1991;7(4-6):245-55.
In a group of 12 subjects with essential hypertension (EH), we evaluated the erythrocyte membrane fluidity and red cell membrane transverse fluidity gradient. We also evaluated the total red cell Ca content, the red cell cytosolic free calcium, the red cell membrane cholesterol/phospholipid ratio and the red cell membrane individual phospholipids. From the data obtained, it is evident that the erythrocyte membrane fluidity and red cell membrane transverse fluidity gradient discriminate normals from hypertensives. None of the red cell metabolic parameters is able, however, to differentiate normals from hypertensive subjects. Our data underline the abnormality of the red cell membrane dynamic properties in hypertension; this abnormality is not, however, related to the red cell metabolic parameters considered.
在一组12名原发性高血压（EH）患者中，我们评估了红细胞膜流动性和红细胞膜横向流动性梯度。我们还评估了红细胞总钙含量、红细胞胞质游离钙、红细胞膜胆固醇/磷脂比率以及红细胞膜单个磷脂。从获得的数据来看，很明显红细胞膜流动性和红细胞膜横向流动性梯度能够区分正常人和高血压患者。然而，没有一个红细胞代谢参数能够区分正常人和高血压患者。我们的数据强调了高血压患者红细胞膜动态特性的异常；然而，这种异常与所考虑的红细胞代谢参数无关。
