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Total red cell calcium content, cytosolic red cell free calcium and erythrocyte membrane dynamic properties in diabetes mellitus.

作者信息

Caimi G, Serra A, Lo Presti R, Grifo G, Romano A, Galluzzo A, Sarno A

机构信息

Insegnamento di Fisiopatologia del Ricambio, Università degli Studi, Palermo, Italy.

出版信息

Microcirc Endothelium Lymphatics. 1991;7(4-6):257-66.

PMID:1815107
Abstract

In a group of diabetics subdivided for type (12 of type 1 and 12 of type 2), we evaluated the total red cell Ca content, red cell cytosolic free calcium, erythrocyte membrane fluidity and erythrocyte membrane protein lateral mobility. From the results obtained, it is evident that the total red cell Ca content does not discriminate normals from type 1 and 2 diabetics, whereas the red cell cytosolic free calcium does differentiate between these diabetic types. Erythrocyte membrane fluidity and erythrocyte protein lateral mobility discriminate normals from type 1 and 2 diabetics. In normals and in diabetics of type 1 and 2, no relationship is evident between total red cell Ca content, membrane fluidity and membrane protein lateral mobility. A slight, but significant negative correlation between red cell cytosolic free calcium values and parameters reflecting the red cell dynamic properties is present in type 2 diabetics only.

摘要

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