Stigen Øyvind, Kolbjørnsen Øyvor
Department of Companion Animal Clinical Sciences, Norwegian School of Veterinary Science, PO Box 8146, 0033 Oslo, Norway.
Acta Vet Scand. 2007 Dec 21;49(1):39. doi: 10.1186/1751-0147-49-39.
The purpose of the study was to compare radiographic and histopathologic findings with regard to number and extent of calcified discs in the dachshund.
The intervertebral discs of 20 dachshunds were subjected to a radiographic and histopathologic examination. The dogs were selected randomly from clinical cases euthanased for reasons unrelated to research at the Norwegian School of Veterinary Science. Lateral radiographs were taken of the vertebral columns after removing them from the carcasses. The histopathologic examination included 5 microm thick sections in the transverse plane, stained with hematoxylin-eosin and von Kossa. Radiographs and histological sections were evaluated independently.
A total of 148 (28.5%) calcified discs were identified at the radiographic and 230 (45.7%) at the histopathologic examination. Of 92 discs found to be calcified by histopathology, but not by radiography, the degree of calcification was evaluated as 'slight' in 84 (91.3%). All the intervertebral discs (n = 138) that were found to be calcified by radiography were also found to be calcified by histopathology.
A sensitivity of 0.6 and specificity of 1.0 for radiography was calculated when using histopathology as the gold standard.
本研究的目的是比较腊肠犬钙化椎间盘的数量和范围的影像学和组织病理学表现。
对20只腊肠犬的椎间盘进行影像学和组织病理学检查。这些犬只从挪威兽医学院因与研究无关的原因实施安乐死的临床病例中随机选取。从尸体上取下脊柱后拍摄侧位X线片。组织病理学检查包括在横断面上制作5微米厚的切片,用苏木精-伊红和冯·科萨染色。X线片和组织学切片分别进行评估。
在影像学检查中总共发现148个(28.5%)钙化椎间盘,在组织病理学检查中发现230个(45.7%)。在组织病理学检查中发现钙化但影像学检查未发现的92个椎间盘中,84个(91.3%)的钙化程度被评估为“轻度”。所有在影像学检查中发现钙化的椎间盘(n = 138)在组织病理学检查中也被发现钙化。
以组织病理学作为金标准时,计算出影像学检查的敏感性为0.6,特异性为1.0。