DiGiorgi Paul L, Baumann F Gregory, O'Leary Anne M, Schwartz Charles F, Grossi Eugene A, Ribakove Greg H, Colvin Stephen B, Galloway Aubrey C, Grau Juan B
Department of Cardiothoracic Surgery, New York University School of Medicine, New York, New York 10016, USA.
Ann Thorac Surg. 2008 Jan;85(1):89-93. doi: 10.1016/j.athoracsur.2007.07.048.
Disparities associated with race, particularly African-American race, in access to medical and surgical care for patients with cardiac disease have previously been documented. The purpose of this study was to determine the presentation, etiology, and hospital outcome differences between African-American patients and white patients with regard to surgically corrected mitral valve disease.
All 1,425 adult patients who underwent first time, isolated mitral valvuloplasty or mitral valve replacement by the same group of surgeons at New York University Medical Center and Bellevue Hospital Center between 1993 and 2003 were studied.
African Americans (n = 123, 8.6%) were significantly younger (45.6 +/- 14.4 versus 60.5 +/- 15.3 years) and had significantly higher incidences of diabetes mellitus, renal failure, congestive heart failure, endocarditis, and rheumatic mitral disease; whereas whites (n = 1,302, 91.4%) more commonly had degenerative mitral disease. African Americans were less likely to undergo mitral valvuloplasty. There were no significant differences in the incidences of postoperative complications or hospital mortality (2.4% African American versus 5.1% white, p = 0.19).
African Americans present for mitral valve surgery at a significantly younger age than whites and with higher incidences of many risk factors. Whether presentation at a significantly earlier age in African Americans is a result of failures in primary care or an enhanced susceptibility to the process of mitral disease and comorbidities remains to be determined. African Americans were less likely to undergo mitral valvuloplasty, which may have an effect on long-term outcome. Improved screening in this racial group will facilitate earlier referral, increasing the potential for mitral valvuloplasty.
先前已有文献记载,在获得心脏病患者的医疗和外科治疗方面,存在与种族相关的差异,尤其是非裔美国人。本研究的目的是确定接受手术矫正二尖瓣疾病的非裔美国患者和白人患者在临床表现、病因及住院结局方面的差异。
对1993年至2003年间在纽约大学医学中心和贝尔维尤医院中心由同一组外科医生进行首次单纯二尖瓣成形术或二尖瓣置换术的1425例成年患者进行研究。
非裔美国人(n = 123,8.6%)明显更年轻(45.6±14.4岁对60.5±15.3岁),糖尿病、肾衰竭、充血性心力衰竭、心内膜炎和风湿性二尖瓣疾病的发病率显著更高;而白人(n = 1302,91.4%)更常见退行性二尖瓣疾病。非裔美国人接受二尖瓣成形术的可能性较小。术后并发症发生率或住院死亡率无显著差异(非裔美国人2.4%对白人5.1%,p = 0.19)。
非裔美国人接受二尖瓣手术的年龄明显比白人年轻,且许多危险因素的发病率更高。非裔美国人在明显更早的年龄出现这种情况是初级保健失败的结果,还是对二尖瓣疾病和合并症进程的易感性增强,仍有待确定。非裔美国人接受二尖瓣成形术的可能性较小,这可能会对长期结局产生影响。改善对该种族群体的筛查将有助于更早转诊,增加二尖瓣成形术的可能性。