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美国结构性心脏病干预措施的使用情况及治疗结果中的种族差异。

Racial Disparities in the Utilization and Outcomes of Structural Heart Disease Interventions in the United States.

作者信息

Alkhouli Mohamad, Alqahtani Fahad, Holmes David R, Berzingi Chalak

机构信息

Division of Cardiology Department of Medicine West Virginia University Morgantown WV.

Department of Cardiology Mayo Clinic School of Medicine Rochester MN.

出版信息

J Am Heart Assoc. 2019 Aug 6;8(15):e012125. doi: 10.1161/JAHA.119.012125. Epub 2019 Jul 18.

Abstract

Background Data on race- and ethnicity-based disparities in the utilization and outcomes of structural heart disease interventions in the United States are scarce. Methods and Results We used the National Inpatient Sample (2011-2016) to examine racial and ethnic differences in the utilization, in-hospital outcomes, and cost of structural heart disease interventions among patients ≥65 years of age. A total of 106 119 weighted hospitalizations for transcatheter aortic valve replacement, transcatheter mitral valve repair, and left atrial appendage occlusion were included. The utilization rates (defined as the number of procedures performed per 100 000 US people >65 years of age) were higher in whites compared with blacks and Hispanics for transcatheter aortic valve replacement (43.1 versus 18.0 versus 21.1), transcatheter mitral valve repair (5.0 versus 3.2 versus 3.2), and left atrial appendage occlusion (6.6 versus 2.1 versus 3.5), respectively (P<0.001). Black and Hispanic patients had distinctive socioeconomic and clinical risk profiles compared with white patients. There were no significant differences in the adjusted in-hospital mortality or key complications between patients of white race, black race, and Hispanic ethnicity following transcatheter aortic valve replacement, transcatheter mitral valve repair, or left atrial appendage occlusion. No difference in cost was observed between white and black patients following any of the 3 procedures. However, Hispanic patients incurred modestly higher cost with transcatheter mitral valve repair and left atrial appendage occlusion compared with white patients. Conclusions Racial and ethnic disparities exist in the utilization of structural heart disease interventions in the United States. Nonetheless, adjusted in-hospital outcomes were comparable among white, black, and Hispanic patients. Further studies are needed to understand the reasons for these utilization disparities.

摘要

背景

在美国,关于结构性心脏病干预措施的使用及治疗结果方面基于种族和民族的差异的数据很少。

方法与结果

我们使用全国住院患者样本(2011 - 2016年)来研究65岁及以上患者在结构性心脏病干预措施的使用、住院结局和费用方面的种族和民族差异。总共纳入了106119例经导管主动脉瓣置换术、经导管二尖瓣修复术和左心耳封堵术的加权住院病例。经导管主动脉瓣置换术(43.1对18.0对21.1)、经导管二尖瓣修复术(5.0对3.2对3.2)和左心耳封堵术(6.6对2.1对3.5)的使用率(定义为每10万名65岁以上美国人中进行的手术例数),白人高于黑人和西班牙裔(P<0.001)。与白人患者相比,黑人和西班牙裔患者有独特的社会经济和临床风险特征。在经导管主动脉瓣置换术、经导管二尖瓣修复术或左心耳封堵术后,白人、黑人及西班牙裔患者在调整后的住院死亡率或关键并发症方面没有显著差异。在这三种手术中的任何一种之后,白人和黑人患者之间未观察到费用差异。然而,与白人患者相比,西班牙裔患者在经导管二尖瓣修复术和左心耳封堵术上的费用略高。

结论

在美国,结构性心脏病干预措施的使用存在种族和民族差异。尽管如此,白人、黑人和西班牙裔患者调整后的住院结局具有可比性。需要进一步研究以了解这些使用差异的原因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e81/6761641/4b70ad6c71b0/JAH3-8-e012125-g001.jpg

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