Wang Vincent Y, Potts Matt, Chou Dean
Department of Neurological Surgery, University of California, 505 Parnassus Avenue, Room M779, San Francisco, CA 94143-0112, USA.
Neurosurg Clin N Am. 2008 Jan;19(1):71-80. doi: 10.1016/j.nec.2007.10.001.
Primary sarcomas are rare in the spine. Common primary sarcomas include osteosarcoma, Ewing's sarcoma, chondrosarcomas, and retroperitoneal soft-tissue sarcomas. These tumors tend to occur in adolescents and young adults. Surgery remains the mainstay of treatment, although the anatomy of spine and spinal cord often limits complete surgical resection with a wide margin. Chemotherapy and radiation therapy have variable effects on these tumors. With recent advances in surgical techniques and development of new chemotherapy protocols, survival and local control are both improving.
原发性肉瘤在脊柱中较为罕见。常见的原发性肉瘤包括骨肉瘤、尤因肉瘤、软骨肉瘤和腹膜后软组织肉瘤。这些肿瘤往往发生在青少年和年轻成年人中。手术仍然是主要的治疗方法,尽管脊柱和脊髓的解剖结构常常限制了广泛切缘的完整手术切除。化疗和放疗对这些肿瘤的效果各不相同。随着手术技术的最新进展和新化疗方案的开发,生存率和局部控制率都在提高。