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脱细胞组织移植物增强术对急性跟腱断裂影响的初步研究

A preliminary study on the effects of acellular tissue graft augmentation in acute Achilles tendon ruptures.

作者信息

Lee Daniel K

机构信息

Department of Orthopaedic Surgery, University of California, San Diego, 350 Dickinson St, MC 8894, San Diego, CA 92103, USA.

出版信息

J Foot Ankle Surg. 2008 Jan-Feb;47(1):8-12. doi: 10.1053/j.jfas.2007.08.015. Epub 2007 Oct 29.

DOI:10.1053/j.jfas.2007.08.015
PMID:18156058
Abstract

Acute Achilles tendon rupture injuries present surgical challenges because of the mechanical forces placed on this tendon. The purpose of this study was to evaluate the effectiveness of an acellular human dermal tissue matrix, GraftJacket Matrix (Wright Medical Technology, Inc., Arlington, TN), as an augmentation material in acute Achilles tendon repair. Eleven consecutive patients with acute tendon ruptures were evaluated and followed up (20-31 months). Primary repair was followed by augmentation with the graft sutured circumferentially around the tendon. Patients were placed in an early functional rehabilitation program with postoperative evaluation at 3, 6, and 12 months. Outcome scores were calculated based on the American Orthopaedic Foot and Ankle Society ankle-hindfoot scoring system. At 20-month postoperative follow-up, there have been no cases of rerupture or recurrent pain. The average return-to-activity time was 11.8 +/- 0.75 weeks. These retrospective clinical results suggest that with an acellular human dermal tissue matrix to augment acute Achilles tendon, primary repair offers a desirable return-to-activity time without any rerupture or complications. ACFAS Level of Clinical Evidence: 2c.

摘要

急性跟腱断裂损伤由于作用于该肌腱的机械力而带来手术挑战。本研究的目的是评估一种脱细胞人真皮组织基质GraftJacket基质(Wright Medical Technology, Inc., Arlington, TN)作为急性跟腱修复中增强材料的有效性。对11例连续的急性肌腱断裂患者进行了评估和随访(20 - 31个月)。在初次修复后,用移植物围绕肌腱进行环周缝合增强。患者被纳入早期功能康复计划,并在术后3个月、6个月和12个月进行评估。根据美国矫形足踝协会踝 - 后足评分系统计算结果评分。术后20个月随访时,无再断裂或复发性疼痛病例。平均恢复活动时间为11.8±0.75周。这些回顾性临床结果表明采用脱细胞人真皮组织基质增强急性跟腱的初次修复可提供理想的恢复活动时间,且无再断裂或并发症。美国矫形足踝协会临床证据等级:2c。

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