Lopes Gildete Barreto, Martins Maria Tereza Silveira, Matos Cácia Mendes, Amorim Josete Leão de, Leite Eneida Barreto, Miranda Eva Alves, Lopes Antonio Alberto
Coordenação central Núcleo de Epidemiologia Clínica, Hospital Universitário Professor Edgard Santos Salvador, Faculdade de Medicina, Universidade Federal da Bahia, Salvador, BA.
Rev Assoc Med Bras (1992). 2007 Nov-Dec;53(6):506-9. doi: 10.1590/s0104-42302007000600017.
To compare men and women on chronic hemodialysis in relation to their scores in health-related quality of life (HRQOL) and evaluate the potential influence of age and comorbidities on the comparison.
Cross-section of the baseline data of 254 women and 349 men, participants of the PROHEMO Study that has been developed in dialysis units of Salvador. By using the version of the Kidney Disease Quality of Life Short Form KDQOL-SF, validated for the Brazilian population, the following scores were determined: physical component summary (PCS), mental component summary [MCS] and the scale for symptoms/problems related to renal disease. The PCS and MCS scores were derived from the eight generic KDQOL-SF scales. Multiple linear regression was used to estimate differences in the scores of men and women (DS), adjusted for age, years on hemodialysis, heart failure, cerebrovascular disease, peripheral vasculopathy, diabetes, serum hemoglobin and serum albumin.
Mean ages were 48.1+/-14.1 and 49.4+/-14.0 years for women and men, respectively. Women had lower scores for all generic HRQOL scales. They also had significantly (P<0.001) lower scores for PCS (DS=2.4 points), MCS (DS=3 points) and symptoms/problems (DS = 6.6 points). Differences were independent of comorbidties and greater in the group over 49 years of age.
Data indicate that for several scales of HRQOL, women treated chronically by hemodialysis had lower scores than men. Lower scores in women were observed for different age groups, independently of comorbidities.
比较接受慢性血液透析的男性和女性在健康相关生活质量(HRQOL)方面的得分,并评估年龄和合并症对该比较的潜在影响。
对参与在萨尔瓦多透析单位开展的PROHEMO研究的254名女性和349名男性的基线数据进行横断面分析。使用经过巴西人群验证的肾脏病生活质量简表(KDQOL-SF)版本,确定以下得分:身体成分总结(PCS)、心理成分总结(MCS)以及与肾脏疾病相关的症状/问题量表。PCS和MCS得分来自KDQOL-SF的八个通用量表。采用多元线性回归估计男性和女性得分的差异(DS),并对年龄、血液透析年限、心力衰竭、脑血管疾病、外周血管病变、糖尿病、血清血红蛋白和血清白蛋白进行校正。
女性和男性的平均年龄分别为48.1±14.1岁和49.4±14.0岁。女性在所有通用HRQOL量表上的得分均较低。她们在PCS(DS = 2.4分)、MCS(DS = 3分)和症状/问题(DS = 6.6分)方面的得分也显著较低(P<0.001)。差异与合并症无关,且在49岁以上的人群中更大。
数据表明,在几种HRQOL量表上,接受慢性血液透析治疗的女性得分低于男性。在不同年龄组的女性中均观察到较低得分,且与合并症无关。