Samura Kazuhiro, Morioka Takato, Yoshida Fumiaki, Hashiguchi Kimiaki, Miyagi Yasushi, Mizoguchi Masahiro, Shono Tadahisa, Nagata Shinji, Suzuki Satoshi O, Sasaki Tomio
Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
Childs Nerv Syst. 2008 May;24(5):619-22. doi: 10.1007/s00381-007-0566-4. Epub 2007 Dec 22.
Focal cortical dysplasia (FCD) with calcification is rare. We presented a 13-year-old epileptic patient with FCD and calcification in the left frontal lobe. At age 24, the FCD lesion and the surrounding epileptogenic cortex and underlying subcortex were removed after chronic subdural electrode recording. Histological examination showed that the calcified lesion was not independent of the FCD lesion but located in the subcortical area of the FCD lesion. A neoplastic nature was ruled out for the lesion.
The pathophysiological mechanism involved in the coexistence of FCD and calcification is discussed.
