Halgrimson Whitney R, Campsen Jeffrey, Mandell M Susan, Kelly Mara A, Kam Igal, Zimmerman Michael A
Division of Transplant Surgery, University of Colorado Health Sciences Center, P.O. Box 6510, Aurora, CO 80045I, USA.
J Transplant. 2010;2010:825689. doi: 10.1155/2010/825689. Epub 2010 Jan 6.
standard laparoscopic donor nephrectomy (LDN) and hand-assisted laparoscopic donor nephrectomy (HALDN). In this study we report the operative statistics and donor complications associated with LDN and HALDN from large-center peer-reviewed publications. Methods. We conducted PubMed and Ovid searches to identify LDN and HALDN outcome studies that were published after 2004. Results. There were 37 peer-reviewed studies, each with more than 150 patients. Cumulatively, over 9000 patients were included in this study. LDN donors experienced a higher rate of intraoperative complications than HALDN donors (5.2% versus. 2.0%, P < .001). Investigators did not report a significant difference in the rate of major postoperative complications between the two groups (LDN 0.5% versus HALDN 0.7%, P = .111). However, conversion to open procedures from vascular injury was reported more frequently in LDN procedures (0.8% versus 0.4%, P = .047). Conclusion. At present there is no evidence to support the use of one laparoscopic approach in preference to the other. There are trends in the data suggesting that intraoperative injuries are more common in LDN while minor postoperative complications are more common in HALDN.
标准腹腔镜供体肾切除术(LDN)和手辅助腹腔镜供体肾切除术(HALDN)。在本研究中,我们报告了来自大型中心经同行评审的出版物中与LDN和HALDN相关的手术统计数据和供体并发症。方法。我们进行了PubMed和Ovid检索,以确定2004年后发表的LDN和HALDN结局研究。结果。有37项经同行评审的研究,每项研究有超过150名患者。累计共有超过9000名患者纳入本研究。LDN供体术中并发症发生率高于HALDN供体(5.2%对2.0%,P <.001)。研究人员未报告两组术后主要并发症发生率有显著差异(LDN为0.5%对HALDN为0.7%,P = 0.111)。然而,LDN手术中因血管损伤转为开放手术的情况报告更为频繁(0.8%对0.4%,P = 0.047)。结论。目前没有证据支持优先使用一种腹腔镜方法而非另一种。数据中有趋势表明,LDN术中损伤更常见,而HALDN术后轻微并发症更常见。