Frewen Paul, Lane Richard D, Neufeld Richard W J, Densmore Maria, Stevens Todd, Lanius Ruth
London Health Sciences Centre, 339 Windermere Road, London, Ontario, Canada, N6A 5A5.
Psychosom Med. 2008 Jan;70(1):27-31. doi: 10.1097/PSY.0b013e31815f66d4. Epub 2007 Dec 24.
To examine individual differences in levels of emotional awareness as a predictor of the blood oxygenation level dependent (BOLD) response to trauma script-driven imagery in trauma-exposed individuals with (n = 25) and without (n = 16) posttraumatic stress disorder (PTSD).
Participants completed the Levels of Emotional Awareness Scale (LEAS) and a functional magnetic resonance imaging trauma script-driven imagery paradigm.
Patients with PTSD exhibited lower LEAS scores in comparison with the control group. LEAS scores correlated positively with BOLD activity during trauma script-imagery in the ventral anterior cingulate cortex (vACC) in healthy controls, whereas LEAS scores correlated negatively with activation of vACC in individuals with PTSD.
Patients with PTSD exhibit lower than average levels of emotional awareness. Levels of emotional awareness are differentially associated with vACC response during trauma script-driven imagery in healthy controls versus individuals with PTSD.
研究情绪觉察水平的个体差异，以此作为创伤暴露个体（有创伤后应激障碍（PTSD）者n = 25例，无PTSD者n = 16例）对创伤脚本驱动意象的血氧水平依赖（BOLD）反应的预测指标。
参与者完成情绪觉察水平量表（LEAS）及功能性磁共振成像创伤脚本驱动意象范式。
与对照组相比，PTSD患者的LEAS得分更低。在健康对照组中，LEAS得分与创伤脚本意象期间腹侧前扣带回皮质（vACC）的BOLD活动呈正相关，而在PTSD个体中，LEAS得分与vACC的激活呈负相关。
PTSD患者的情绪觉察水平低于平均水平。在健康对照组与PTSD个体中，情绪觉察水平与创伤脚本驱动意象期间vACC反应的相关性存在差异。
