Hwang Young Tae, Shin Jung Woo, Lee Jun Ho, Hwang Dae Sung, Eum Jun Bum, Choi Hye Jeong, Park Neung Hwa
Department of Internal Medicine, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, Korea.
Korean J Hepatol. 2007 Dec;13(4):565-70. doi: 10.3350/kjhep.2007.13.4.565.
Although liver metastasis is commonly found in cancer patients, fulminant hepatic failure secondary to diffuse cancer infiltration into the liver is rare. Liver metastasis-induced fulminant hepatic failure has been reported in patients with primary cancer of the gastrointestinal tract, breast and uroepithelium, and in patients with melanoma and hematologic malignancy. Small cell lung cancer is so highly invasive that hepatic metastasis is common, but rapid progression to fulminant hepatic failure is extremely rare. We report here on a case of a patient who died because of rapid progression to fulminant hepatic failure as a result of hepatic metastasis of small cell lung carcinoma.
尽管肝转移在癌症患者中很常见,但因弥漫性癌浸润肝脏继发的暴发性肝衰竭却很罕见。胃肠道、乳腺和尿路上皮原发性癌患者,以及黑色素瘤和血液系统恶性肿瘤患者中,均有肝转移导致暴发性肝衰竭的报道。小细胞肺癌侵袭性很强,肝转移很常见,但迅速进展为暴发性肝衰竭极为罕见。我们在此报告一例小细胞肺癌肝转移导致迅速进展为暴发性肝衰竭而死亡的患者。