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是否应将矮腰果(Anacardium humile St. Hil)用作抗溃疡剂?对传统知识的科学探索。

Should Anacardium humile St. Hil be used as an antiulcer agent? A scientific approach to the traditional knowledge.

作者信息

Luiz-Ferreira Anderson, Cola-Miranda Maira, Barbastefano Victor, Hiruma-Lima Clélia Akiko, Vilegas Wagner, Souza Brito Alba Regina Monteiro

机构信息

Departamento de Fisiologia e Biofísica, Universidade Estadual de Campinas (UNICAMP), Campinas, SP, Brazil.

出版信息

Fitoterapia. 2008 Apr;79(3):207-9. doi: 10.1016/j.fitote.2007.11.006. Epub 2007 Nov 28.

DOI:10.1016/j.fitote.2007.11.006
PMID:18164871
Abstract

The crude methanolic extract (ME) obtained from the leaves of Anacardium humile was evaluated orally at doses of 250-500-1000 mg/kg on gastric lesion on ethanol and piroxicam induced gastric lesions in rodents. All the tested doses significantly inhibited gastric lesions by 56 to 100%. These results seems to support the traditional use of this species in the treatment of gastric diseases.

摘要

从腰果树叶中提取的粗甲醇提取物(ME),以250 - 500 - 1000毫克/千克的剂量经口给药,用于评估其对啮齿动物乙醇诱导的胃损伤和吡罗昔康诱导的胃损伤的影响。所有测试剂量均显著抑制胃损伤,抑制率为56%至100%。这些结果似乎支持了该物种在治疗胃部疾病方面的传统用途。

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