Kumanov Philip, Robeva Ralitsa N, Tomova Analia
Clinical Center of Endocrinology, Medical University-Sofia, 6, Dame Gruev str, 1303, Sofia, Bulgaria.
Pediatrics. 2008 Jan;121(1):e53-7. doi: 10.1542/peds.2007-0340.
Varicocele results from the abnormal dilation of the veins of the pampiniform plexus and is the most common identifiable cause of male infertility. It can develop during puberty and thus affect the testicular growth and function. The aim of this study was to determine the prevalence and the risk factors for the development of the varicocele among Bulgarian boys.
In a prospective study, 6200 boys from 5 regions of the country aged 0 to 19 years were evaluated for varicocele. All were clinically healthy. Height, weight, testicular volumes, penile length, and penile circumference were also examined.
Varicocele was found in 4.1% of all investigated boys, whereas in the age group 10 to 19 years, it was 7.9%. After adjustment for age, the negative factors associated with the development of the disorder were height, penile length, and penile circumference, whereas the weight and BMI had a protective role. The prevalence of varicocele demonstrated clear regional differences, and it was found significantly more often among dark-eyed boys. The incidence of the disease increased rapidly during midpuberty.
The incidence of varicocele is related to some somatometric parameters and with the accelerated pubertal development. Longitudinal studies are needed to clarify better the relations between the adolescent varicocele and puberty.
精索静脉曲张是由蔓状静脉丛的静脉异常扩张引起的，是男性不育最常见的可识别原因。它可在青春期发生，从而影响睾丸的生长和功能。本研究的目的是确定保加利亚男孩中精索静脉曲张的患病率及其发生的危险因素。
在一项前瞻性研究中，对该国5个地区6200名年龄在0至19岁的男孩进行了精索静脉曲张评估。所有男孩临床均健康。还检查了身高、体重、睾丸体积、阴茎长度和阴茎周长。
在所有接受调查的男孩中，4.1%发现患有精索静脉曲张，而在10至19岁年龄组中，这一比例为7.9%。在对年龄进行调整后，与该疾病发生相关的负面因素是身高、阴茎长度和阴茎周长，而体重和体重指数具有保护作用。精索静脉曲张的患病率存在明显的地区差异，在黑眼睛男孩中更为常见。该疾病的发病率在青春期中期迅速上升。
精索静脉曲张的发病率与一些身体测量参数以及青春期发育加速有关。需要进行纵向研究以更好地阐明青少年精索静脉曲张与青春期之间的关系。
