Meave Aloha, Soto Maria E, Reyes Pedro A, Cruz Patricio, Talayero Jose A, Sierra Carlos, Alexanderson Erick
Department of Nuclear Cardiology, Instituto Nacional de Cardiología Ignacio Chávez, México City, Mexico.
Tex Heart Inst J. 2007;34(4):466-9.
Takayasu's arteritis is a primary vasculitis that affects large vessels and is characterized by chronic granulomatous inflammation. Diagnosis has been primarily clinical, with verification by angiography as the gold standard. More recently, however, it has become apparent that positron emission tomography enables better evaluation of vascular inflammation. This study presents 2 cases of Takayasu's arteritis. Magnetic resonance angiography was used to evaluate aortic anatomy by analyzing vascular wall thickness and also to quantify disease activity by measuring gadolinium enhancement. Positron emission tomography was used to evaluate active vascular inflammation by quantifying fluorodeoxyglucose F18 uptake. We conclude that both techniques support clinical diagnosis and aid in the evaluation of disease activity during and after treatment.
高安动脉炎是一种影响大血管的原发性血管炎，其特征为慢性肉芽肿性炎症。诊断主要依靠临床，血管造影作为金标准进行验证。然而，最近正电子发射断层扫描已明显能够更好地评估血管炎症。本研究展示了2例高安动脉炎病例。通过分析血管壁厚度，磁共振血管造影用于评估主动脉解剖结构，并通过测量钆增强来量化疾病活动度。正电子发射断层扫描通过量化氟脱氧葡萄糖F18摄取来评估活动性血管炎症。我们得出结论，这两种技术均支持临床诊断，并有助于评估治疗期间及治疗后的疾病活动度。
