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六味生精汤治疗少弱精子症的临床观察

[Clinical observation on treatment of oligospermia and asthenospermia with Liuwu Shengjing Decoction].

作者信息

Guo Jun, Song Chun-sheng, Geng Qiang

机构信息

Department of Andrology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing.

出版信息

Zhongguo Zhong Xi Yi Jie He Za Zhi. 2007 Nov;27(11):986-8.

PMID:18173142
Abstract

OBJECTIVE

To investigate the clinical efficacy and safety of Liuwu Shengjing Decoction (LWD) in treating oligospermia and asthenospermia.

METHODS

One hundred and fourteen patients were randomized into two groups, the treated group administrated with self-formulated LWD, and the control group administrated with Wuzi Yanzong Pill (WYP). All were treated for 3 months. Patients' semen was analyzed before and after treatment, and the therapeutic efficacy was evaluated.

RESULTS

The total effective rate was 94.8% in the treated group, with a partner pregnant rate of 8.6% (5/58), while in the control group, they were 85.7% and 5.4% (3/56) respectively. The efficacy in the treated group was better (P = 0.03). Patients' sperm count and viability of sperm were improved in both groups (P < 0.05 or P < 0.01), but the improvement in the treated group was superior (P < 0.05).

CONCLUSION

LWD could effectively improve the condition of male infertility with oligospermia and asthenospermia.

摘要

目的

探讨六味生精汤治疗少弱精子症的临床疗效及安全性。

方法

将114例患者随机分为两组,治疗组服用自拟六味生精汤,对照组服用五子衍宗丸。两组均治疗3个月。治疗前后对患者精液进行分析,并评估治疗效果。

结果

治疗组总有效率为94.8%,配偶妊娠率为8.6%(5/58);对照组总有效率为85.7%,配偶妊娠率为5.4%(3/56)。治疗组疗效更佳(P = 0.03)。两组患者的精子计数和精子活力均有所改善(P < 0.05或P < 0.01),但治疗组改善更明显(P < 0.05)。

结论

六味生精汤能有效改善男性少弱精子症不育状况。

相似文献

1
[Clinical observation on treatment of oligospermia and asthenospermia with Liuwu Shengjing Decoction].六味生精汤治疗少弱精子症的临床观察
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2007 Nov;27(11):986-8.
2
[Effect of modified tianxiong powder in treating oligospermia and asthenospermia].
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2010 May;30(5):496-8.
3
Clinical observations on therapeutic effects of the modified shengjing zhongzi tang (see text) in patients with asthenospermia and oligozoospermia.生精种子汤加减治疗少弱精子症临床观察。
J Tradit Chin Med. 2011 Sep;31(3):192-4. doi: 10.1016/s0254-6272(11)60040-x.
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[Effect of zengjing no. 1 capsule on morphology and motility of sperm in patients with oligospermia].
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2009 Nov;29(11):1029-30.
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[Clinical observation on electroacupuncture and Chinese drug for treatment of oligospermia and asthenospermia of the male infertility patient].
Zhongguo Zhen Jiu. 2008 Nov;28(11):805-7.
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[Male infertility with severe oligospermatism and azoospermia treated by Bushen Shengjing Decoction combined with intracytoplasmic sperm injection].
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2007 Nov;27(11):972-5.
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[Clinical efficacy of Yangjing Decoction on idiopathic asthenozoospermia].养精汤治疗特发性弱精子症的临床疗效
Zhonghua Nan Ke Xue. 2010 Jun;16(6):569-71.
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[Multi-centered clinical trial of Fufang Xuanju capsule for oligoasthenospermia].复方玄驹胶囊治疗少弱精子症的多中心临床试验
Zhonghua Nan Ke Xue. 2008 Aug;14(8):755-8.
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[Comparison of clinical efficacy between Huorongbushen and indomethacin in patients with oligospermia or asthenospermia].[蠲荣补渗与吲哚美辛治疗少精子症或弱精子症患者的临床疗效比较]
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[Clinical study on treatment of male infertility with shengjing pill].
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1
Effectiveness of Peng's Shengjing recipe on male asthenospermia caused by kidney yang deficiency: A randomized pilot study.彭氏生精方治疗肾阳不足型弱精症的有效性:一项随机试点研究。
Saudi Med J. 2023 Mar;44(3):253-259. doi: 10.15537/smj.2023.44.3.20220676.
2
A Chinese herbal formula, Wuzi Yanzong pill, improves spermatogenesis by modulating the secretory function of Sertoli cells.一种中药配方五子衍宗丸,通过调节支持细胞的分泌功能来改善精子发生。
Chin J Integr Med. 2014 Mar;20(3):194-9. doi: 10.1007/s11655-014-1743-4. Epub 2014 Mar 4.