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显微内镜下椎间盘切除术在减少医源性肌肉损伤方面的疗效。

The efficacy of microendoscopic discectomy in reducing iatrogenic muscle injury.

作者信息

Shin Dong Ah, Kim Keung Nyun, Shin Hyun Cheol, Yoon Do Heum

机构信息

Department of Neurosurgery, Spine and Spinal Cord Institute, Yonsei University College of Medicine, Seoul, Republic of Korea.

出版信息

J Neurosurg Spine. 2008 Jan;8(1):39-43. doi: 10.3171/SPI-08/01/039.

Abstract

OBJECT

The objective of this study was to evaluate the invasiveness of microendoscopic discectomy (MED) in comparison with microscopic discectomy (MD) by measuring serum levels of creatine phosphokinase (CPK)-MM and lactate dehydrogenase (LDH)-5, and by comparing visual analog scale (VAS) scores of postoperative pain.

METHODS

This study included a group of 15 patients who underwent surgery using MED and 15 patients who underwent surgery using MD, both for single-level unilateral herniated nucleus pulposus. The CPK-MM and LDH-5 levels were measured at admission and after 1, 3, and 5 days postoperatively. Pain assessment was recorded using scores raging from 0 to 10 on a subjective VAS at admission and at 1, 3, and 5 days postoperatively.

RESULTS

The mean CPK-MM levels were lower for the MED group than for the MD group at both 3 (576.1 +/- 286.3 IU/L compared with 968.1 +/- 377.8 IU/L) and 5 days (348.1 +/- 231.0 IU/L compared with 721.7 +/- 463.2) postoperatively (p < 0.05). The mean VAS scores for postoperative back pain were lower in the MED group than in the MD group, both at 1 (3.3 +/- 2.3 compared with 5.8 +/- 1.5) and 5 days (1.9 +/- 1.1 compared with 3.6 +/- 1.1) postoperatively (p < 0.01).

CONCLUSIONS

The MED procedure is less invasive than MD, and causes less muscle damage and less back pain.

摘要

目的

本研究的目的是通过测量血清肌酸磷酸激酶(CPK)-MM和乳酸脱氢酶(LDH)-5水平,并比较术后疼痛的视觉模拟量表(VAS)评分,来评估显微内镜下椎间盘切除术(MED)与显微镜下椎间盘切除术(MD)相比的侵袭性。

方法

本研究纳入了15例行MED手术的患者和15例行MD手术的患者,两组均为单节段单侧髓核突出。在入院时以及术后1、3和5天测量CPK-MM和LDH-5水平。使用主观VAS在入院时以及术后1、3和5天记录疼痛评估,评分范围为0至10分。

结果

MED组术后3天(分别为576.1±286.3 IU/L和968.1±377.8 IU/L)和5天(分别为348.1±231.0 IU/L和721.7±463.2)的平均CPK-MM水平低于MD组(p<0.05)。MED组术后1天(分别为3.3±2.3和5.8±1.5)和5天(分别为1.9±1.1和3.6±1.1)的术后背痛平均VAS评分低于MD组(p<0.01)。

结论

MED手术的侵袭性低于MD,且造成的肌肉损伤和背痛更少。

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