Lu Peng, Chen Xiaoming, Kang Ying, Ke Lang, Wei Xiaoyan, Zhang Wenfang
Ophthalmology Department, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Clin Exp Ophthalmol. 2007 Dec;35(9):828-33. doi: 10.1111/j.1442-9071.2007.01630.x.
To describe the prevalence and to identify associated risk factors for pterygium in a Tibetan population at high altitude in Zeku County, China.
A prospective population-based survey was conducted from October to December 2006. A stratified, clustered, randomized sampling procedure was used to select 2632 Tibetan people aged 40 years and older. Pterygium was diagnosed and graded clinically as grade 1 (transparent), 2 (intermediate) and 3 (opaque). Risks factors associated with pterygium were evaluated with logistic regression models.
From a total of 2632 eligible subjects, 2229 (84.69%) were examined. There were 323 people with pterygium, equivalent to an overall prevalence of 14.49% (95% confidence interval [CI] 13.03-15.95). Pterygium was independently associated with increasing age for persons aged 70-79 years, compared with those aged 40-49 years (odds ratio [OR] 2.0; 95% CI 1.4-2.8), female gender (OR 1.6; 95% CI 1.2-2.0), dry eye symptoms (OR 1.3; 95% CI 1.0-1.7), seldom use of sunglasses/crystal spectacles (OR 4.6; 95% CI 1.9-11.3) or hats (OR 3.6: 95% CI 2.4-5.4), lower education level (<3 years) (OR 1.6; 95% CI 1.1-2.4) and low socioeconomic status (OR 1.9; 95% CI 1.5-2.4).
The prevalence of pterygium in a Tibetan population at high altitude is significantly high, particularly in certain at-risk groups. The primary causative factors are related to ocular sun exposure, which are easily preventable. Public health schemes to address this serious health issue are urgently needed.
描述中国泽库县高海拔地区藏族人群中翼状胬肉的患病率，并确定相关危险因素。
2006年10月至12月进行了一项基于人群的前瞻性调查。采用分层、整群、随机抽样程序，选取2632名40岁及以上的藏族人。翼状胬肉通过临床诊断并分为1级（透明）、2级（中间型）和3级（不透明）。使用逻辑回归模型评估与翼状胬肉相关的危险因素。
在总共2632名符合条件的受试者中，2229名（84.69%）接受了检查。有323人患有翼状胬肉，总体患病率为14.49%（95%置信区间[CI]13.03 - 15.95）。与40 - 49岁的人相比，70 - 79岁的人患翼状胬肉与年龄增长独立相关（优势比[OR]2.0；95%CI 1.4 - 2.8），女性（OR 1.6；95%CI 1.2 - 2.0），干眼症状（OR 1.3；95%CI 1.0 - 1.7），很少使用太阳镜/水晶眼镜（OR 4.6；95%CI 1.9 - 11.3）或帽子（OR 3.6：95%CI 2.4 - 5.4），教育水平较低（<3年）（OR 1.6；95%CI 1.1 - 2.4）和社会经济地位较低（OR 1.9；95%CI 1.5 - 2.4）。
高海拔地区藏族人群中翼状胬肉的患病率显著较高，尤其是在某些高危人群中。主要致病因素与眼部阳光暴露有关，这些因素易于预防。迫切需要公共卫生计划来解决这一严重的健康问题。
