Dayan Gustavo H, Caquías Carmen Rodríguez, García Yaniré, Malik Tasneem, Copeland John, Bi Daoling, Reef Susan
Epidemiology and Surveillance Division, National Immunization Program, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Paediatr Perinat Epidemiol. 2008 Jan;22(1):31-9. doi: 10.1111/j.1365-3016.2007.00873.x.
Recommendations for screening for maternal infections and interventions to prevent disease in the fetus or newborn have been in place in Puerto Rico for more than 10 years. However, compliance with these recommendations has not been widely documented. We evaluated compliance with rubella/hepatitis B prenatal screening and vaccination recommendations, assessed hospital screening practices for syphilis and HIV, and determined risk factors for suboptimal prenatal care. Records of a random, stratified sample of 2003 pregnant women delivering in eight maternity hospitals in Puerto Rico in 2002 were reviewed. Obstetric prenatal and postnatal records were also reviewed when rubella/hepatitis B surface antigen (HBsAg) screening was not available at the hospital, and to document rubella postpartum vaccination (PPV). Prenatal screening rates were 98.4% for rubella and 98.8% for HBsAg. Overall, 5.4% [95% CI 4.4, 6.5] of women were susceptible to rubella. No eligible women received rubella PPV at the hospital and only 1.5% had documented rubella vaccine prescription at the obstetric records. Only one woman was found to be HBsAg positive and her newborn was adequately treated. However, only 0.9% newborns born to mothers with unknown HBsAg status received hepatitis B vaccine. Screening was documented in 85.7% of the hospital records for HIV and 87.9% for syphilis. Suboptimal prenatal care was more likely among teenagers, low-educated women, and women with >3 previous pregnancies. Screening rates for rubella and hepatitis B were high; however, implementation of recommendations for prevention of rubella and hepatitis B needs to be improved.
在波多黎各,针对孕妇感染筛查及预防胎儿或新生儿疾病干预措施的建议已实施超过10年。然而,这些建议的依从性尚未得到广泛记录。我们评估了风疹/乙肝产前筛查及疫苗接种建议的依从性,评估了医院梅毒和艾滋病毒的筛查做法,并确定了产前护理欠佳的风险因素。回顾了2002年在波多黎各八家妇产医院分娩的2003名孕妇的随机分层样本记录。当医院无法进行风疹/乙肝表面抗原(HBsAg)筛查时,还查阅了产科产前和产后记录,以记录风疹产后疫苗接种(PPV)情况。风疹产前筛查率为98.4%,HBsAg筛查率为98.8%。总体而言,5.4%[95%可信区间4.4, 6.5]的女性对风疹易感。医院中没有符合条件的女性接受风疹PPV,产科记录中只有1.5%有风疹疫苗处方记录。仅发现一名女性HBsAg呈阳性,其新生儿得到了充分治疗。然而,HBsAg状态不明的母亲所生的新生儿中只有0.9%接种了乙肝疫苗。85.7%的医院记录中有艾滋病毒筛查记录,87.9%有梅毒筛查记录。青少年、低学历女性以及既往有3次以上妊娠的女性产前护理欠佳的可能性更大。风疹和乙肝的筛查率很高;然而,预防风疹和乙肝建议的实施情况仍需改善。