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无创性脑干监测:眼球微震颤

Non-invasive brainstem monitoring: the ocular microtremor.

作者信息

Robertson James, Timmons Shelly

机构信息

Department of Neurosurgery, The University of Tennessee Health Science Center, Memphis, TN 38163, USA.

出版信息

Neurol Res. 2007 Oct;29(7):709-11. doi: 10.1179/016164107X240198.

DOI:10.1179/016164107X240198
PMID:18173910
Abstract

The ocular microtremor (OMT) is mediated by the oculomotor area of the brainstem and is altered in several pathologic states, including traumatic brain injury, general anesthesia, brain death, coma, Parkinsonism and multiple sclerosis. The EYETECT tremor monitor is a non-invasive means of measuring the frequency and amplitude of this microscopic tremor. It has been clinically tested in these clinical scenarios and has been found to be a reliable means of detecting the depth of anesthesia, and has been useful in predicting outcome in coma and traumatic brain injury patients and in confirming brain death. This paper reviews the scientific literature on the EYETECT OMT monitor, describes the underlying physiology and discusses the potential for future works and clinical use of this innovative technology.

摘要

眼球微震颤(OMT)由脑干的动眼神经区域介导,在多种病理状态下会发生改变,包括创伤性脑损伤、全身麻醉、脑死亡、昏迷、帕金森病和多发性硬化症。EYETECT震颤监测仪是一种测量这种微小震颤频率和幅度的非侵入性方法。它已在这些临床场景中进行了临床测试,被发现是检测麻醉深度的可靠手段,并且在预测昏迷和创伤性脑损伤患者的预后以及确认脑死亡方面很有用。本文回顾了关于EYETECT OMT监测仪的科学文献,描述了其潜在的生理学原理,并讨论了这项创新技术未来研究和临床应用的潜力。

相似文献

1
Non-invasive brainstem monitoring: the ocular microtremor.无创性脑干监测:眼球微震颤
Neurol Res. 2007 Oct;29(7):709-11. doi: 10.1179/016164107X240198.
2
[Spectral analyses in ocular microtremor in disorders of brain stem function].[脑干功能障碍时眼微震颤的频谱分析]
EEG EMG Z Elektroenzephalogr Elektromyogr Verwandte Geb. 1987 Mar;18(1):20-6.
3
Superior oblique myokymia. Report and discussion on five cases of benign intermittent uniocular microtremor.上斜肌肌纤维颤搐。5例良性间歇性单眼微震颤的报告与讨论。
Arch Ophthalmol. 1970 Oct;84(4):461-7. doi: 10.1001/archopht.1970.00990040463011.
4
Ocular microtremor in oculomotor palsy.动眼神经麻痹中的眼球微震颤。
J Neuroophthalmol. 1999 Mar;19(1):42-5.
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Ocular microtremor: a tool for measuring depth of anaesthesia?眼球微震颤:一种测量麻醉深度的工具?
Br J Anaesth. 2001 Apr;86(4):519-22. doi: 10.1093/bja/86.4.519.
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Ocular microtremor during general anesthesia: results of a multicenter trial using automated signal analysis.全身麻醉期间的眼球微震颤:一项使用自动信号分析的多中心试验结果
Anesth Analg. 2004 Sep;99(3):775-780. doi: 10.1213/01.ANE.0000133145.98702.C0.
7
Harmaline-induced tremor. II. Unit activity correlation in the interposito-rubral and oculomotor systems of cat.骆驼蓬碱诱发的震颤。II. 猫中介核-红核及动眼系统中的单位活动相关性
Exp Brain Res. 1981;42(3-4):383-91. doi: 10.1007/BF00237503.
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High frequency eye tremor: reliability of measurement.高频眼震:测量的可靠性
Clin Phys Physiol Meas. 1992 May;13(2):151-9. doi: 10.1088/0143-0815/13/2/007.
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Effect of age on ocular microtremor activity.年龄对眼微震颤活动的影响。
J Gerontol A Biol Sci Med Sci. 2001 Jun;56(6):M386-90. doi: 10.1093/gerona/56.6.m386.
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Ocular microtremor (OMT): a new neurophysiological approach to multiple sclerosis.眼球微震颤(OMT):一种针对多发性硬化症的新神经生理学方法。
J Neurol Neurosurg Psychiatry. 2000 May;68(5):639-42. doi: 10.1136/jnnp.68.5.639.

引用本文的文献

1
Digital measurement of ocular microtremor in Parkinson's disease: Protocol for a pilot study to assess reliability and clinical validation.帕金森病中眼球微震颤的数字测量:一项评估可靠性和临床验证的试点研究方案。
PLoS One. 2025 Jan 8;20(1):e0313452. doi: 10.1371/journal.pone.0313452. eCollection 2025.