DiFazio Marc P, Braun Loranee, Freedman Scott, Hickey Patrick
Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
J Child Neurol. 2007 Dec;22(12):1367-70. doi: 10.1177/0883073807307083.
Rotavirus infection is a frequent cause of gastroenteritis in children and accounts for significant morbidity and mortality, especially in the developing world. Less well recognized is the association of rotavirus-induced central nervous system dysfunction, which has been associated with seizure, encephalopathy, and death. Symptoms may vary widely, however, and children can experience short afebrile convulsions as the only manifestation of rotavirus encephalopathy. We report 4 further cases of rotavirus-induced seizures with mild neurologic manifestations. The condition is reviewed and practical management strategies are suggested.
轮状病毒感染是儿童肠胃炎的常见病因，会导致显著的发病率和死亡率，在发展中世界尤其如此。轮状病毒引起的中枢神经系统功能障碍的关联较少被认识到，这种功能障碍与癫痫、脑病和死亡有关。然而，症状可能差异很大，儿童可能仅以短暂的无热惊厥作为轮状病毒脑病的唯一表现。我们报告了另外4例轮状病毒引起的伴有轻度神经学表现的癫痫病例。本文对该病症进行了综述并提出了实际的管理策略。
