Kadimova E
A. Aliev Azerbaidjan State Institute of Physician's Professional Improvement, Baku, Azerbaidjan.
Georgian Med News. 2007 Nov(152):35-7.
Often thalassaemia patients have significant iron stores. The present research has been conducted to estimate a level of the overall store and degree of an iron overload in patients suffering from beta-thalassemia in pre- and post-surgery periods (pre-surgery, and to the second, seventh, fifteenth, and thirtieth days) after splenectomy. Observation was conducted once a year. The observation period was eight years. The analysis of parameters of iron metabolism in patients with beta-thalassemia in the distant period of time after splenectomy showed that the decrease of serum iron level and index of transferrin saturation was unchanged during the first year. The index of serum ferittin was unchanged during two years. SFT value remained reduced within a year; two years after splenectomy this parameter reached a preoperative level. The index of total serum coupling capacity remaind unchanged during the whole period of observation. The research revealed, that splenectomy has a positive effect on iron balance.
地中海贫血患者通常有大量铁储存。本研究旨在评估脾切除术前及术后（术前、术后第二天、第七天、第十五天和第三十天）β地中海贫血患者的总体铁储存水平和铁过载程度。每年进行一次观察。观察期为八年。对脾切除术后远期β地中海贫血患者铁代谢参数的分析表明，血清铁水平和转铁蛋白饱和度指数在第一年没有变化。血清铁蛋白指数在两年内没有变化。血清铁结合力（SFT）值在一年内持续降低；脾切除术后两年该参数恢复到术前水平。总血清结合能力指数在整个观察期内保持不变。研究表明，脾切除对铁平衡有积极影响。
