Coprean D, Giurgea R, Tamaş M, Roşca M, Coprean D, Cuparencu B
Biological Research Center Cluj-Napoca, Romania.
Rev Roum Physiol (1990). 1991 Jan-Jun;28(1-2):23-6.
In alloxan-induced diabetes in rats a marked increase in fasting glycemia was seen. The administration of "Hipogalegin" (0.45 g/kg b.w.; for one administration) led to a marked decrease of the glycemia in fasted diabetic animals: 40% of the diabetic animals subjected to this treatment survived and continued to survive even on the 94th day after diabetes was induced. Diabetic animals who were not given "Hypogalegin" died during the first two weeks after diabetes was induced.
在大鼠四氧嘧啶诱导的糖尿病模型中，空腹血糖显著升高。给予“希波格列金”（0.45克/千克体重；单次给药）可使禁食的糖尿病动物血糖显著降低：接受该治疗的糖尿病动物中有40%存活下来，甚至在诱导糖尿病后的第94天仍继续存活。未给予“希波格列金”的糖尿病动物在诱导糖尿病后的头两周内死亡。
