卓越帕里木（Parinari excelsa）树皮水提取物对四氧嘧啶诱导的糖尿病大鼠的抗糖尿病特性。
Antidiabetic properties of aqueous barks extract of Parinari excelsa in alloxan-induced diabetic rats.
作者信息
Ndiaye M, Diatta W, Sy A N, Dièye A M, Faye B, Bassène E
机构信息
Laboratoire de Pharmacologie, Faculté de Médecine, de Pharmacie et d'Odontostomatologie, Université Cheikh Anta Diop, Dakar, Senegal.
出版信息
Fitoterapia. 2008 Jun;79(4):267-70. doi: 10.1016/j.fitote.2008.01.004. Epub 2008 Feb 9.
The aqueous extract of the Parinari excelsa barks at doses of 100 and 300 mg/kg/day for 7 days has a significant antihyperglycemic effect on alloxan-induced diabetic rats. At the same dose the acute oral administration of aqueous extract of the P. excelsa barks (100 and 300 mg/kg) induced a significant decrease of blood glucose on glucose-loaded normoglycaemic rats. Our results seem to confirm the rational bases for its use in traditional medicine.
每天以100和300毫克/千克的剂量给四瓣核果木树皮的水提取物连续服用7天，对四氧嘧啶诱导的糖尿病大鼠具有显著的降血糖作用。以相同剂量对正常血糖的葡萄糖负荷大鼠急性口服四瓣核果木树皮的水提取物（100和300毫克/千克）可使血糖显著降低。我们的结果似乎证实了其在传统医学中应用的合理依据。
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