Gustafsson P, Thernlund G, Besjakov J, Karlsson M K, Ericsson I, Svedin C G
Department of Child and Adolescent Psychiatry, Lund University, Lund, Sweden.
Acta Paediatr. 2008 Feb;97(2):233-8. doi: 10.1111/j.1651-2227.2007.00608.x. Epub 2008 Jan 3.
To study if age and non-behavioural measures of biological maturity have any associations with attention deficit hyperactivity disorder (ADHD).
Two hundred fifty-one children 7 to 9 years of age in a Swedish school were screened for ADHD-symptom. ADHD-symptoms were estimated by Conners Abbreviated Questionnaire by both parents and teachers. Motor function, body weight and body height were measured. Skeletal age was estimated through hand radiographs.
Height, weight and skeletal bone-age did correlate significantly with age (rs = 0.44-0.69, p < 0.001) but not with ADHD symptom scores. Motor dysfunction had a weak negative correlation with age (rs =-0.21, p < 0.05). Parent and teacher scores of ADHD-symptoms did not correlate with age.
This study showed that the variables measuring general biological maturity had a strong association with age, whereas motor dysfunction and ADHD symptoms had no significant association with age. ADHD symptoms did not correlate with the variables measuring general biological maturity. These results do not support the hypothesis that a general biological immaturity is an important etiologic factor for ADHD symptomatology.
研究年龄和生物成熟度的非行为测量指标是否与注意力缺陷多动障碍（ADHD）存在关联。
对瑞典一所学校的251名7至9岁儿童进行ADHD症状筛查。ADHD症状由父母和教师通过康纳斯简明问卷进行评估。测量运动功能、体重和身高。通过手部X光片估计骨骼年龄。
身高、体重和骨骼骨龄与年龄显著相关（rs = 0.44 - 0.69，p < 0.001），但与ADHD症状评分无关。运动功能障碍与年龄呈弱负相关（rs = -0.21，p < 0.05）。父母和教师对ADHD症状的评分与年龄无关。
本研究表明，测量一般生物成熟度的变量与年龄密切相关，而运动功能障碍和ADHD症状与年龄无显著关联。ADHD症状与测量一般生物成熟度的变量无关。这些结果不支持一般生物不成熟是ADHD症状学重要病因的假说。
