Lanchares Elena, Calvo Begoña, Cristóbal José A, Doblaré Manuel
Aragón Institute of Engineering Research , University of Zaragoza , Spain.
J Biomech. 2008;41(4):797-805. doi: 10.1016/j.jbiomech.2007.11.010. Epub 2008 Jan 3.
In order to simulate the corneal incisions used to correct astigmatism, a three-dimensional finite element model was generated from a simplified geometry of the anterior half of the ocular globe. A hyperelastic constitutive behavior was assumed for cornea, limbus and sclera, which are collagenous materials with a fiber structure. Due to the preferred orientations of the collagen fibrils, corneal and limbal tissues were considered anisotropic, whereas the sclera was simplified to an isotropic one assuming that fibrils are randomly disposed. The reference configuration, which includes the initial strain distribution that balances the intraocular pressure, is obtained by an iterative process. Then the incisions are simulated. The final positions of the nodes belonging to the incised meridian and to the perpendicular one are fitted by both radii of curvature, which are used to calculate the optical power. The simulated incisions were those specified by Lindstrom's nomogram [Chu, Y., Hardten, D., Lindquist, T., Lindstrom, R., 2005. Astigmatic keratotomy. Duane's Ophthalmology. Lippincott Williams and Wilkins, Philadelphia] to achieve 1.5, 2.25, 3.0, 4.5 and 6.0D of astigmatic change, using the next values for the parameters: length of 45 degrees , 60 degrees and 90 degrees , an optical zone of 6mm, single or paired incisions. The model gives results similar to those in Lindstrom's nomogram [Chu et al., 2005] and can be considered a useful tool to plan and simulate refractive surgery by predicting the outcomes of different sorts of incisions and to optimize the values for the parameters involved: depth, length, position.
为了模拟用于矫正散光的角膜切口,从简化的眼球前半部分几何结构生成了三维有限元模型。假定角膜、角膜缘和巩膜具有超弹性本构行为,它们是具有纤维结构的胶原质材料。由于胶原纤维的优先取向,角膜和角膜缘组织被视为各向异性,而巩膜则被简化为各向同性,假定纤维是随机排列的。通过迭代过程获得包括平衡眼内压的初始应变分布的参考构型。然后模拟切口。属于切开子午线和垂直子午线的节点的最终位置由两个曲率半径拟合,这两个曲率半径用于计算屈光力。模拟的切口是林德斯特伦列线图[Chu, Y., Hardten, D., Lindquist, T., Lindstrom, R., 2005. 散光角膜切开术。《杜安眼科学》。Lippincott Williams and Wilkins出版社,费城]所规定的那些切口,以实现1.5、2.25、3.0、4.5和6.0D的散光变化,使用以下参数值:45度、60度和90度的长度,6mm的光学区,单切口或双切口情况。该模型给出的结果与林德斯特伦列线图[Chu等人,2005]中的结果相似,并且可被视为一种有用的工具,通过预测不同类型切口的结果来规划和模拟屈光手术,并优化所涉及参数的值:深度、长度、位置。