Malloy Kelly M, Cunnane Mary F
Department of Otolaryngology/Head and Neck Surgery, University of Michigan, 1904 Taubman Health Center, 1500 E. Medical Center Drive, Ann Arbor, MI 48109-0312, USA.
Surg Oncol Clin N Am. 2008 Jan;17(1):57-70, viii. doi: 10.1016/j.soc.2007.10.012.
Most thyroid neoplasms arise from follicular cells and are well differentiated. Anaplastic and poorly differentiated carcinomas are rare and have a high mortality. Five percent of tumors are of C-cell origin, and 20% to 25% of these are hereditary. Thyroid lymphoma is rare and occurs in the setting of Hashimoto's thyroiditis. Fine needle aspiration biopsy is the best diagnostic tool to classify thyroid neoplasms.
大多数甲状腺肿瘤起源于滤泡细胞,且分化良好。未分化癌和低分化癌较为罕见,死亡率很高。5%的肿瘤起源于C细胞,其中20%至25%为遗传性。甲状腺淋巴瘤罕见,发生于桥本甲状腺炎背景下。细针穿刺活检是对甲状腺肿瘤进行分类的最佳诊断工具。