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通过传统剖腹术或超微创手术进行子宫肌瘤切除术治疗的前瞻性短期评估。

A prospective short-term evaluation of uterine leiomyomas treated by myomectomy through conventional laparotomy or ultraminilaparotomy.

作者信息

Wen Kuo-Chang, Sung Pi-Lin, Chao Kuan-Chong, Lee Wen-Ling, Liu Wei-Min, Wang Peng-Hui

机构信息

Department of Obstetrics and Gynecology, Taipei Veterans General Hospital and National Yang-Ming University School of Medicine, Taipei, Taiwan.

出版信息

Fertil Steril. 2008 Dec;90(6):2361-6. doi: 10.1016/j.fertnstert.2007.10.006. Epub 2008 Jan 4.

Abstract

OBJECTIVE

To evaluate the short-term therapeutic outcome of myomectomy through conventional laparotomy in the treatment of uncomplicated uterine myomas compared with myomectomy through ultraminilaparotomy.

DESIGN

Controlled, nonrandomized clinical study.

SETTING

University-affiliated tertiary care referral center.

PATIENT(S): One hundred thirteen patients with symptomatic and uncomplicated uterine myomas warranting surgical treatment, who expressed a strong desire to retain their uterus. Seventy-two patients underwent myomectomy by laparotomy and 41 by ultraminilaparotomy.

INTERVENTION(S): Myomectomy through laparotomy or ultraminilaparotomy access.

MAIN OUTCOME MEASURE(S): The outcome was measured by comparing blood loss, need for blood transfusion, operative time, postoperative febrile morbidity, time of flatus passage after operation, and postoperative pain (visual analogue scale score and anesthesia use) in both groups.

RESULT(S): General characteristics of the patients were similar in both groups. There were no statistical differences in mean operative time, blood loss, febrile morbidity, insurance pay, and therapeutic efficacy (symptom relief) between the two groups. However, postoperative recovery seemed to be better and more rapid in the ultraminilaparotomy group compared with that in the laparotomy group, including rapid and early bowel movement, lower scores on the visual analogue scale, and shortened postoperative hospital stay.

CONCLUSION(S): This study demonstrates the superiority of ultraminilaparotomy in treating uncomplicated uterine myomas, compared with laparotomy, during this 1-year short-term follow-up.

摘要

目的

评估传统剖腹手术子宫肌瘤切除术与超微创剖腹手术子宫肌瘤切除术治疗单纯性子宫肌瘤的短期治疗效果。

设计

对照、非随机临床研究。

地点

大学附属三级医疗转诊中心。

患者

113例有症状的单纯性子宫肌瘤患者需要手术治疗,且强烈希望保留子宫。72例行剖腹子宫肌瘤切除术,41例行超微创剖腹子宫肌瘤切除术。

干预措施

通过剖腹手术或超微创剖腹手术入路行子宫肌瘤切除术。

主要观察指标

通过比较两组患者的失血量、输血需求、手术时间、术后发热发病率、术后排气时间以及术后疼痛(视觉模拟评分和麻醉使用情况)来衡量治疗效果。

结果

两组患者的一般特征相似。两组患者的平均手术时间、失血量、发热发病率、保险支付情况和治疗效果(症状缓解)无统计学差异。然而,与剖腹手术组相比,超微创剖腹手术组术后恢复似乎更好更快,包括肠道蠕动更快更早、视觉模拟评分更低以及术后住院时间缩短。

结论

本研究表明,在这1年的短期随访中,与剖腹手术相比,超微创剖腹手术在治疗单纯性子宫肌瘤方面具有优势。

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