Rattanachaiyanont M, Kuptniratsaikul V
Department of Obstetrics and Gynecology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Thailand.
Osteoarthritis Cartilage. 2008 Jul;16(7):823-8. doi: 10.1016/j.joca.2007.10.013. Epub 2008 Feb 21.
To evaluate the benefit of shortwave diathermy (SWD) supplemented to an exercise program for knee osteoarthritis (OA) in peri-/post-menopausal women.
A double-blind randomized placebo-controlled equivalence trial was conducted in a university hospital. Participants including 113 women aged 50-85 years with primary knee OA were instructed to do regular quadriceps exercise, and randomized to control (n=60) and treatment (n=53) groups receiving sham SWD and therapeutic SWD, respectively. The treatment being evaluated was continuous SWD, 20 min/session, 3 sessions/week for 3 weeks. The outcomes including Thai Western Ontario and McMaster Universities OA (WOMAC) index, 100-m walking speed, stair ascent-and-descent time, global assessment, patient's satisfaction, and adverse events were assessed at baseline and end of treatment.
At the end of treatment, both groups had trivial but statistical improvement in all outcomes. Intention-to-treat analysis showed no statistically significant difference between the two groups in all outcomes. Per protocol analysis demonstrated the equivalence in Thai WOMAC total score, as the 95% confidence interval of difference (-0.62, 0.92) was within confidence limits of +/-1cm.
The addition of SWD to an exercise program for knee OA in peri-/post-menopausal women is not superior to the exercise program alone.
评估短波透热疗法（SWD）辅助运动疗法对围绝经期/绝经后女性膝骨关节炎（OA）的疗效。
在一所大学医院进行了一项双盲随机安慰剂对照等效性试验。113名年龄在50 - 85岁的原发性膝OA女性参与者被指导进行常规股四头肌锻炼，并随机分为对照组（n = 60）和治疗组（n = 53），分别接受假短波透热疗法和治疗性短波透热疗法。所评估的治疗为连续短波透热疗法，每次20分钟，每周3次，共3周。在基线和治疗结束时评估包括泰国西安大略和麦克马斯特大学骨关节炎（WOMAC）指数、100米步行速度、上下楼梯时间、整体评估、患者满意度和不良事件等结果。
治疗结束时，两组在所有结果上均有轻微但具有统计学意义的改善。意向性分析显示两组在所有结果上均无统计学显著差异。符合方案分析表明泰国WOMAC总分具有等效性，因为差异的95%置信区间（-0.62, 0.92）在±1cm的置信限内。
对于围绝经期/绝经后女性膝OA，在运动疗法基础上加用短波透热疗法并不优于单纯运动疗法。
