Fat B Chung, Terzibachian J-J, Govyadovskiy A, Grisey A
Service de gynécologie-obstétrique, centre hospitalier de Belfort-Montbéliard, 14, rue de Mulhouse, 90016 Belfort cedex, France.
Gynecol Obstet Fertil. 2008 Jan;36(1):51-5. doi: 10.1016/j.gyobfe.2007.06.019. Epub 2008 Jan 4.
Malignant transformation of endometriosis is a rare event. The ovaries are the most common sites reported in the literature. Postmenopausal cancer arising in extragenital endometriosis is still more exceptional. Hormone replacement therapy and perhaps, to a lesser extent, Tamoxifen could be risk factors for the malignant transformation of endometriosis. We herein report the case of a patient who has developed, after 11 years of hormone replacement therapy, an extragenital endometrioid carcinoma in the vesico-uterine pouch.
