Applegate C D, Samoriski G M, Burchfiel J L
Comprehensive Epilepsy Program, University of Rochester School of Medicine and Dentistry, NY 14642.
Epilepsy Res. 1991 Nov-Dec;10(2-3):142-7. doi: 10.1016/0920-1211(91)90006-2.
Amygdala kindling was observed to increase significantly the proportion of rats that exhibited tonic hindlimb extension in response to corneal electroshock stimulation. Mechanical brainstem lesions which abolished electroshock-induced tonic hindlimb extension failed to alter either the expression of fully generalized kindled seizures or the development of amygdala kindled seizures. Results suggest that while kindling can alter the sensitivity of brainstem systems involved in the expression of tonic hindlimb extension, these same systems are not necessary for either the development or expression of amygdala kindled seizures.
观察到杏仁核点燃显著增加了对角膜电休克刺激表现出强直性后肢伸展的大鼠比例。消除电休克诱导的强直性后肢伸展的机械性脑干损伤未能改变完全全身性点燃发作的表达或杏仁核点燃发作的发展。结果表明，虽然点燃可以改变参与强直性后肢伸展表达的脑干系统的敏感性，但这些相同的系统对于杏仁核点燃发作的发展或表达并非必需。
