用于叠氮化物与炔烃在环境条件下无添加剂环加成反应的多相铜催化剂。

Heterogeneous copper catalyst for the cycloaddition of azides and alkynes without additives under ambient conditions.

作者信息

Park In Soo, Kwon Min Serk, Kim Youngkwon, Lee Jae Sung, Park Jaiwook

机构信息

Department of Chemistry, Pohang University of Science and Technology (POSTECH), San 31 Hyojadong, Pohang, Kyeongbuk 790-784, Republic of Korea.

出版信息

Org Lett. 2008 Feb 7;10(3):497-500. doi: 10.1021/ol702790w. Epub 2008 Jan 9.

DOI:10.1021/ol702790w

PMID:18181635

Abstract

A new copper catalyst was developed by immobilizing copper nanoparticles in aluminum oxyhydoxide fiber. The catalyst showed high catalytic activity for the (3+2) Huisgen cycloaddition of nonactivated alkynes as well as activated ones with various azides at room temperature. The catalyst was recycled five times without significant loss of activity.

摘要

通过将铜纳米颗粒固定在羟基氧化铝纤维中，开发出了一种新型铜催化剂。该催化剂在室温下对未活化的炔烃以及与各种叠氮化物反应的活化炔烃的（3 + 2）胡伊斯根环加成反应表现出高催化活性。该催化剂可循环使用五次，活性无显著损失。