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金属纳米颗粒(MNPs)在含氮和含氧杂环骨架合成中的应用十年进展。

A decennary update on applications of metal nanoparticles (MNPs) in the synthesis of nitrogen- and oxygen-containing heterocyclic scaffolds.

作者信息

Dhameliya Tejas M, Donga Hiren A, Vaghela Punit V, Panchal Bhoomi G, Sureja Dipen K, Bodiwala Kunjan B, Chhabria Mahesh T

机构信息

L. M. College of Pharmacy Navrangpura Ahmedabad 380 009 Gujarat India

出版信息

RSC Adv. 2020 Sep 3;10(54):32740-32820. doi: 10.1039/d0ra02272a. eCollection 2020 Sep 1.

Abstract

Heterocycles have been found to be of much importance as several nitrogen- and oxygen-containing heterocycle compounds exist amongst the various USFDA-approved drugs. Because of the advancement of nanotechnology, nanocatalysis has found abundant applications in the synthesis of heterocyclic compounds. Numerous nanoparticles (NPs) have been utilized for several organic transformations, which led us to make dedicated efforts for the complete coverage of applications of metal nanoparticles (MNPs) in the synthesis of heterocyclic scaffolds reported from 2010 to 2019. Our emphasize during the coverage of catalyzed reactions of the various MNPs such as Ag, Au, Co, Cu, Fe, Ni, Pd, Pt, Rh, Ru, Si, Ti, and Zn has not only been on nanoparticles catalyzed synthetic transformations for the synthesis of heterocyclic scaffolds, but also provide an inherent framework for the reader to select a suitable catalytic system of interest for the synthesis of desired heterocyclic scaffold.

摘要

人们发现杂环非常重要,因为美国食品药品监督管理局(USFDA)批准的各类药物中存在几种含氮和含氧的杂环化合物。由于纳米技术的进步,纳米催化在杂环化合物的合成中得到了广泛应用。许多纳米颗粒(NPs)已被用于多种有机转化反应,这促使我们致力于全面涵盖2010年至2019年期间报道的金属纳米颗粒(MNPs)在杂环骨架合成中的应用。我们在涵盖各种MNPs(如Ag、Au、Co、Cu、Fe、Ni、Pd、Pt、Rh、Ru、Si、Ti和Zn)的催化反应时,不仅关注纳米颗粒催化的用于杂环骨架合成的合成转化反应,还为读者提供了一个内在框架,以便他们选择适合自己感兴趣的用于合成所需杂环骨架的催化体系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0361/9056690/3c9758c10809/d0ra02272a-f1.jpg

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