Orozco H, Mercado M A, Takahashi T, Chan C, Quintanilla L, Jiménez M, Sosa R, Esquivel E
División de Cirugía, Clínica de Hipertensión Portal, Instituto Nacional de la Nutrición Salvador Zubirán, México, D.F.
Rev Invest Clin. 1991 Jul-Sep;43(3):255-8.
A 15-year-old woman who was studied because an abdominal mass at the Instituto Nacional de la Nutricion Salvador Zubiran (INNSZ) is reported. The history revealed only malaise and mild abdominal pain. At physical exploration, an abdominal mass in the upper right quadrant was found. Liver function tests were normal. Abdominal ultrasound and computerized tomography revealed a large cystic mass of the right hepatic lobe. She underwent exploratory laparotomy. Intraoperative frozen sections of the biopsies demonstrated undifferentiated sarcoma of the liver, and an extended right trisegmentectomy was performed. Postoperative outcome was uneventful. Adjuvant treatment with doxorubicin and dacarbazine was given, and at six months of follow-up, the patient is alive without any evidence of recurrence. Clinical and histopathologic features of this rare malignant tumor are discussed, as well as the therapeutic choices.
报告了一名15岁女性,她因在萨尔瓦多·苏比兰国家营养研究所(INNSZ)发现腹部肿块而接受检查。病史仅显示不适和轻度腹痛。体格检查时,在右上腹发现一个腹部肿块。肝功能检查正常。腹部超声和计算机断层扫描显示右肝叶有一个大的囊性肿块。她接受了剖腹探查术。术中活检的冰冻切片显示为肝脏未分化肉瘤,遂进行了扩大的右三段切除术。术后恢复顺利。给予了阿霉素和达卡巴嗪辅助治疗,随访6个月时,患者存活,无复发迹象。本文讨论了这种罕见恶性肿瘤的临床和组织病理学特征以及治疗选择。