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成人肝脏囊性病变:未分化原发性胚胎性肉瘤的挑战性诊断

Hepatic cystic lesion in adult: a challenging diagnosis of undifferentiated primary embryonal sarcoma.

作者信息

Massani M, Caratozzolo E, Baldessin M, Bonariol L, Bassi N

机构信息

Regional Hospital Cà Foncello, Treviso, Italy.

出版信息

G Chir. 2010 May;31(5):225-8.

Abstract

Cystic lesions of the liver are common. Most of these represent benign simple cysts that generally require no intervention. The diagnosis of simple hepatic cysts is straightforward in the face of typical radiographic findings; however, diagnostic uncertainty, based solely on radiographic criteria alone, is not an uncommon clinical dilemma. In this report, we present a case of a 47 old woman with a cystic liver lesion and acute epigastric pain. The patient had no previous history of oral contraceptive assumption or liver disease. A tender mass was palpable on the upper right quadrant of the abdomen. The abdominal ultrasound (US) showed a cystic lesion with a possible hemorrhagic component on right liver lobe. Abdominal computed tomography (CT) and magnetic resonance (MR) revealed a complex cystic lesion with possible intracystic hemorrhage. The patient was submitted to operation and resection; the final histologic diagnosis revealed a primary undifferentiated embryonal sarcoma of the liver. She relapsed 24 months after a new hepatic resection and chemo-embolization, she is alive at 29 months after first surgery.

摘要

肝脏囊性病变很常见。其中大多数为良性单纯囊肿,通常无需干预。面对典型的影像学表现,单纯性肝囊肿的诊断很简单;然而,仅基于影像学标准的诊断不确定性在临床中并非罕见的困境。在本报告中,我们介绍了一例47岁女性,患有肝脏囊性病变并伴有急性上腹部疼痛。该患者既往无口服避孕药史或肝脏疾病史。在腹部右上象限可触及一个压痛性肿块。腹部超声(US)显示右肝叶有一个可能伴有出血成分的囊性病变。腹部计算机断层扫描(CT)和磁共振成像(MR)显示一个复杂的囊性病变,可能存在囊内出血。患者接受了手术切除;最终组织学诊断为原发性肝脏未分化胚胎性肉瘤。在进行新的肝脏切除和化疗栓塞后24个月复发,首次手术后29个月仍存活。

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