Chibana Kenji, Touyama Masato, Fujita Jiro
Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases, Faculty of Medicine, University of the Ryukyus.
Nihon Kokyuki Gakkai Zasshi. 2007 Dec;45(12):992-6.
A 58-year-old man with cough and bloody sputum was admitted because of right lung tumor and thrombocytopenia. Idiopathic thrombocytopenic purpura (ITP) was diagnosed. For treatment of ITP, he was treated with platelet transfusions, intravenous gamma-globulin and oral prednisolone. However, the platelet count did not completely improved. Since a relationship between ITP and Helicobacter pylori (HP) infection has been reported, and result of urease test was positive, the patient was treated by HP eradication therapy. After the eradication therapy, the platelet count improved to the normal range. The diagnosis of squamous cell carcinoma of the lung was confirmed by a cervical lymph node biopsy. As a result of improvement in platelet count, we were able to perform the chemotherapy of lung cancer.
一名58岁男性因咳嗽、咯血痰，伴右肺肿瘤及血小板减少入院。诊断为特发性血小板减少性紫癜（ITP）。针对ITP，给予患者血小板输注、静脉注射丙种球蛋白及口服泼尼松龙治疗。然而，血小板计数并未完全改善。由于已有报道称ITP与幽门螺杆菌（HP）感染有关，且尿素酶试验结果为阳性，遂对该患者进行了HP根除治疗。根除治疗后，血小板计数恢复至正常范围。经颈部淋巴结活检确诊为肺鳞状细胞癌。由于血小板计数有所改善，得以对肺癌进行化疗。
