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一名肺移植受者的皮肤ustus曲霉感染:一种新的机会性真菌病原体的出现。

Cutaneous Aspergillus ustus in a lung transplant recipient: emergence of a new opportunistic fungal pathogen.

作者信息

Vagefi Parsia A, Cosimi A Benedict, Ginns Leo C, Kotton Camille N

机构信息

Division of Transplant Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA.

出版信息

J Heart Lung Transplant. 2008 Jan;27(1):131-4. doi: 10.1016/j.healun.2007.09.020.

Abstract

Opportunistic fungal infections remain a significant complication in immunosuppressed patients, especially those having undergone solid-organ transplantation. We report a 39-year-old patient who represents the second case of cutaneous Aspergillus ustus infection in a solid-organ transplant recipient, and the first documented case after lung transplantation. The patient's cutaneous lower extremity aspergillosis responded to a combination of intravenous liposomal amphotericin B, caspofungin and topical terbinafine cream, with a concomitant reduction in immunosuppression. A. ustus is an emerging opportunistic fungal pathogen in transplant recipients.

摘要

机会性真菌感染仍然是免疫抑制患者,尤其是实体器官移植患者的一个重要并发症。我们报告了一名39岁的患者,他是实体器官移植受者中第二例皮肤土曲霉感染病例,也是肺移植后第一例有记录的病例。该患者的下肢皮肤曲霉病对静脉注射脂质体两性霉素B、卡泊芬净和外用特比萘芬乳膏的联合治疗有反应,同时免疫抑制有所减轻。土曲霉是移植受者中一种新出现的机会性真菌病原体。

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