由ustus曲霉引起的皮肤感染，ustus曲霉是免疫抑制患者中一种新出现的机会性真菌。
Cutaneous infection caused by Aspergillus ustus, an emerging opportunistic fungus in immunosuppressed patients.
作者信息
Gené J, Azón-Masoliver A, Guarro J, De Febrer G, Martínez A, Grau C, Ortoneda M, Ballester F
机构信息
Unitat de Microbiologia, Facultat de Medicina i Ciències de la Salut, Hospital Universitari de Sant Joan, 43201-Reus, Tarragona, Spain.
出版信息
J Clin Microbiol. 2001 Mar;39(3):1134-6. doi: 10.1128/JCM.39.3.1134-1136.2001.
Abstract
We report a case of primary cutaneous infection by the emerging fungus Aspergillus ustus in an immunosuppressed patient after a domestic accident. The patient failed to respond to itraconazole and died before receiving a new treatment with amphotericin B. There have been eight other cases reported since 1973, and only two patients survived the infection. In vitro susceptibility testing of seven antifungal drugs showed that terbinafine and the new azole derivative UR-9825 were the most active against this fungus.
摘要
我们报告了一例在家庭事故后免疫抑制患者中由新出现的真菌ustus曲霉引起的原发性皮肤感染病例。该患者对伊曲康唑治疗无反应，在接受两性霉素B新治疗前死亡。自1973年以来已报告了其他8例病例，只有2例患者感染后存活。对7种抗真菌药物的体外药敏试验表明，特比萘芬和新的唑类衍生物UR-9825对这种真菌最具活性。
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