谢氏曲霉（曼金）汤姆和丘奇：一种人类皮肤曲霉病的新型机会致病菌。
Aspergillus chevalieri (Mangin) Thom and Church: a new opportunistic pathogen of human cutaneous aspergillosis.
作者信息
Naidu J, Singh S M
机构信息
Department of Biological Sciences, Rani Durgawati University, Jabalpur, India.
出版信息
Mycoses. 1994 Jul-Aug;37(7-8):271-4. doi: 10.1111/j.1439-0507.1994.tb00425.x.
Three cases of opportunistic cutaneous aspergillosis caused by Aspergillus chevalieri are described. The lesions were erythematous and hyperkeratotic with vesicopapular eruptions and scaling. Histopathology revealed granulomatous reaction showing polymorphonuclear leucocytes around fungal hyphae, which were broad, septate, branched and aggregated in the epidermal area. Oxiconazole and amorolfine, with a minimum inhibitory concentration of 10 micrograms ml-1, were the most active drugs against A. chevalieri 'in vitro'. A. chevalieri is, for the first time, documented as opportunistic pathogen of man.
本文描述了3例由谢瓦曲霉引起的机会性皮肤曲霉病。皮损表现为红斑、角化过度，伴有水疱丘疹性皮疹及脱屑。组织病理学显示肉芽肿反应，真菌菌丝周围可见多形核白细胞，菌丝粗大、有隔膜、分支且聚集于表皮区域。奥昔康唑和阿莫罗芬对谢瓦曲霉的最低抑菌浓度为10微克/毫升，是“体外”对该菌最有效的药物。谢瓦曲霉首次被记录为人类机会性病原体。
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